More than one way to TRIM a capsid
نویسندگان
چکیده
منابع مشابه
More than one way to TRIM a capsid.
A ntibodies protect against lethal infection by bacteria or nonenveloped viruses such as adenovirus (1). They are secreted by plasma cells at the rate of thousands of molecules per second, and it has long been assumed that they function exclusively in the extracellular milieu. The recent discovery of a cytoplasmic process called antibody-dependent intracellular neutralization (ADIN) put an end ...
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D ramatic changes accompany the death of cells. Attempts to align these changes into cognate groups and identify the mechanisms responsible for them have led to substantial and sometimes surprising insights into cell biology. One such constellation of structural and functional changes is associated with apoptosis (a death process found in development, atrophy, the targets of cell killing by the...
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ow cells connect to each other and to the extracellular matrix (ECM) was a sticky issue in the early 1980s. Integrins, molecules that hook the cy-toskeleton to ECM proteins such as collagen and fibronectin, hadn't been discovered, but evidence for a link between external and internal fibers was mounting. For example, Irwin Singer (1979) observed that extra-cellular fibronectin molecules closely...
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We hooked the 5th wheel and boat to the truck for the 240-mile drive to Salmon Falls Creek Reservoir for a walleye tournament. The reservoir is between Twin Falls, Idaho and Jackpot, Nevada. We always look forward to fishing this tournament as it’s a good walleye fishery and we have a lot of friends in the area. We pulled into the federal camp ground at the lake at noon on June 10 and were look...
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The vast majority of eukaryotic messenger mRNAs undergo 30 end cleavage and polyadenylation. The noncanonical poly(A) polymerase (PAP), STAR-PAP, adds a poly(A) tail to specific transcripts under oxidative stress conditions. These transcripts have the AAUAAA polyadenylation signal and use the same factors for cleavage, but are not polyadenylated by the canonical polyA polymerase. In this issue ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1217596109